Vaccination Strategies Against Highly Variable Pathogens – eBook
- Authors: Lars Hangartner, Dennis R. Burton
- File Size: 4 MB
- Format: PDF
- Length: 187 Pages
- Publisher: Springer; 1st edition
- Publication Date: September 1, 2020
- Language: English
- ASIN: B08H879MMH
- ISBN-10: 3030580032, 3030580040
- ISBN-13: 9783030580032, 9783030580049
Given its scope, Vaccination Strategies Against Highly Variable Pathogens, (PDF) will appeal to scientists in the fields of infectious diseases, microbiology, and medicine. Vaccines against antigenically stable pathogens, or pathogens that are only present in a limited number of serotypes, have been very effective in the past and have drastically decreased the incidence and lethality of many diseases. Though, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the conventional methods for vaccine development have reached their limits.
This volume stresses the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, featuring structure-guided vaccine development and vaccines targeting glycans, in addition to adjuvants and animal models used for testing possible vaccine candidates are defined and discussed in detail.
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